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A novel four-component reaction for the synthesis of disubstituted 1,3,4-oxadiazole derivatives

✍ Scribed by Ali Ramazani; Nahid Shajari; Amir Mahyari; Yavar Ahmadi


Publisher
Springer
Year
2010
Tongue
English
Weight
248 KB
Volume
15
Category
Article
ISSN
1381-1991

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## Abstract Reactions of electron‐poor α‐haloketones with (__N__‐isocyanimino) triphenylphosphorane in the presence of aromatic carboxylic acids proceed smoothly at room temperature and in neutral conditions to afford disubstituted 1,3,4‐oxadiazole derivatives in high yields. Β© 2010 Wiley Periodica