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A novel flow cytometric assay for quantitation and multiparametric characterization of cell-mediated cytotoxicity

✍ Scribed by Hervé Lecoeur; Michèle Février; Sylvie Garcia; Yves Rivière; Marie-Lise Gougeon

Book ID: 114050756
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 822 KB
Volume: 253
Category: Article
ISSN: 0022-1759
DOI: 10.1016/s0022-1759(01)00359-3

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Background: Mast cells are primary mediators of allergic inflammation. Antigen-mediated crosslinking of their cell surface immunoglobulin E (IgE) receptors results in degranulation and the release of proinflammatory mediators including histamine, tumor necrosis factor-␣, and leukotrienes. Methods: M