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A Novel EPAC-Specific Inhibitor Suppresses Pancreatic Cancer Cell Migration and Invasion

✍ Scribed by Almahariq, M.; Tsalkova, T.; Mei, F. C.; Chen, H.; Zhou, J.; Sastry, S. K.; Schwede, F.; Cheng, X.

Book ID: 121371767
Publisher: American Society for Pharmacology and Experimental Therapeutics
Year: 2012
Tongue: English
Weight: 860 KB
Volume: 83
Category: Article
ISSN: 0026-895X
DOI: 10.1124/mol.112.080689

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## Abstract Pancreatic cancer is a leading cause of cancer‐related mortality and often has a poor prognosis because of its late diagnosis, aggressive local invasion, early metastasis and poor response to chemotherapy. The chemotherapeutic agent gemcitabine is effective for treating advanced pancrea