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A Novel Enantioselective Alkylation and Its Application to the Synthesis of an Anticancer Agent

✍ Scribed by Kuo, Shen-Chun; Chen, Frank; Hou, Donald; Kim-Meade, Agnes; Bernard, Charles; Liu, Jinchu; Levy, Stacy; Wu, George G.


Book ID
120631001
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
187 KB
Volume
68
Category
Article
ISSN
0022-3263

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Synthesis of a Novel Chiral Ionic Liquid
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## Abstract A novel chiral ionic liquid, compound **1**, based on camphorsulfonic acid, was prepared. A catalytic amount of **1** readily promotes L‐proline‐catalyzed aldol reactions, with good chemoselectivity, both in H~2~O and in organic solvents. Further, the aldol reaction of cyclohexanone wit