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A Novel Docetaxel-Loaded Poly (ε-Caprolactone)/Pluronic F68 Nanoparticle Overcoming Multidrug Resistance for Breast Cancer Treatment

✍ Scribed by Lin Mei; Yangqing Zhang; Yi Zheng; Ge Tian; Cunxian Song; Dongye Yang; Hongli Chen; Hongfan Sun; Yan Tian; Kexin Liu; Zhen Li; Laiqiang Huang

Book ID: 107470557
Publisher: Springer-Verlag
Year: 2009
Tongue: English
Weight: 416 KB
Volume: 4
Category: Article
ISSN: 1931-7573
DOI: 10.1007/s11671-009-9431-6

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A novel paclitaxel-loaded poly(ε-caprolactone)/Poloxamer 188 blend nanoparticle overcoming multidrug resistance for cancer treatment

✍ Yangqing Zhang; Lina Tang; Leilei Sun; Junbo Bao; Cunxian Song; Laiqiang Huang; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 562 KB

Multidrug resistance (MDR) of tumor cells is a major obstacle to the success of cancer chemotherapy. Poloxamers have been used in cancer therapy to overcome MDR. The objective of this research is to test the feasibility of paclitaxel-loaded poly(epsilon-caprolactone)/Poloxamer 188 (PCL/Poloxamer 188