A novel DMAP-promoted oxazolidinethione deacylation. Application for the direct conversion of the initial chiral thioimide aldols to various ester protecting groups

✍ Scribed by Dah-Wei Su; Ying-Chuan Wang; Tu-Hsin Yan

• Book ID: 104261493
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 121 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)00710-8

✦ Synopsis

DMAP (4-(dimethylamino)pyridine) promoted nucleophilic cleavage of the initial chiral thioimide aldols can be directed to form various ester protecting groups without causing racemization of the newly created stereocenters.