𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Novel Dimeric Podophyllotoxin-Type Lignan and a New Withanolide from Withania coagulans

✍ Scribed by M. Nur-e-Alam; Muhummed Yousaf; Samina Qureshi; Irfan Baig; Shama Nasim; Atta-ur-Rahman; M. Iqbal Choudhary

Publisher
John Wiley and Sons
Year
2003
Tongue
German
Weight
101 KB
Volume
86
Category
Article
ISSN
0018-019X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A novel dimeric lignan, bispicropodophyllin glucoside (1) and a highly oxygenated new withanolide, coagulin S (2) were isolated from the ethanolic extract of Withania coagulans. The structures were established on the basis of the spectroscopic data and have been identified as (5__S__*,5a__R__*,8a__R__*,9__S__*,15__S__*,15a__S__*,18a__S__*,19__S__*)‐9,19‐di‐β‐D‐glucopyranosyl‐5,8a,9,15,15a,18,18a,19‐octahydro‐5,15‐bis(3,4,5‐trimethoxyphenyl)bis([1,3]dioxolo[4′,5′:6,7]naphtho)[2,3‐c:2,3‐h][1,6]dioxecin‐6,16(5a__H,8__H)‐dione (1) and (20__S__*,22__R__*)‐5__α__,6__β__,14__α__,15__α__,17__β__,20,27‐heptahydroxy‐1‐oxowith‐24‐enolide (2), respectively.

📜 SIMILAR VOLUMES

Coagulansins A and B, New Withanolides f
Coagulansins A and B, New Withanolides from Withania coagulansDunal
✍ Erum Jahan; Shagufta Perveen; Itrat Fatima; Abdul Malik 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 German ⚖ 154 KB

## Abstract Coagulansins A (**1**) and B (**2**), two new withanolides, were isolated from the CHCl~3~‐soluble fraction of __Withania coagulans__ Dunal, along with two known withanolides, coagulin R and withanolide P. Their structures were assigned by means of ^1^H‐ and ^13^C‐NMR spectra, DEPT, and