A novel dehydrodipeptide synthesis by the reaction of α-triethoxyphosphinimino-α-alkenoates with L-leucyl chlorides

✍ Scribed by Yasuchika Yonezawa; Chung-gi Shin; Mitsunori Kiyohara; Juji Yoshimura

• Publisher: Elsevier Science
• Year: 1979
• Tongue: French
• Weight: 201 KB
• Volume: 20
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)95541-8

✦ Synopsis

A new useful method for the synthesis of dehydropeptide by the reaction of L-leucyl chloride with a-triethoxyphosphinimino-a-alkenoic acids, derived from ethyl a-azido-a-alkenoates and triethyl phosphite, is described.

We have previously reported the facile synthesis of ethyl (Z)-a-azido-a-