A NOVEL CROSSTALK BETWEEN PROTEASOMAL PROTEIN DEGRADATION AND SRF-DEPENDENT GENE TRANSCRIPTION IN VASCULAR SMOOTH MUSCLE CELLS

Suppression of NF-κB-dependent gene expr

Suppression of NF-κB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells

✍ Rika Ouchida; Masatoshi Kusuhara; Noriaki Shimizu; Tetsuya Hisada; Yuichi Makino 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 472 KB

## Abstract **Background:** Neointima formation is a characteristic feature of atherosclerosis and post‐angioplasty restenosis, in which various soluble factors and mechanical injury stimulate signalling pathways in vascular smooth muscle cells (VSMC), promoting their migration and proliferation, a