✦ LIBER ✦

A novel constitutively active mutation in the second cytoplasmic loop of metabotropic glutamate receptor

✍ Scribed by Takahiro Yamashita; Toshihiro Kai; Akihisa Terakita; Yoshinori Shichida

Book ID: 111178515
Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 477 KB
Volume: 91
Category: Article
ISSN: 0022-3042
DOI: 10.1111/j.1471-4159.2004.02739.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A mutation in the second intracellular l

A mutation in the second intracellular loop of the pituitary adenylate cyclase activating polypeptide type I receptor confers constitutive receptor activation

✍ Yong-Jiang Cao; Gerald Gimpl; Falk Fahrenholz 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 181 KB

Activation of metabotropic glutamate rec

Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

✍ P. Jeffrey Conn; Craig W. Lindsley; Carrie K. Jones 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 527 KB

Target-cell-specific concentration of a

Target-cell-specific concentration of a metabotropic glutamate receptor in the presynaptic active zone

✍ Shigemoto, Ryuichi; Kulik, Akos; Roberts, J. David B.; Ohishi, Hitoshi; Nusser, 📂 Article 📅 1996 🏛 Nature Publishing Group 🌐 English ⚖ 913 KB

A novel mutation within the extracellula

A novel mutation within the extracellular domain of TrkA causes constitutive receptor activation

✍ Arevalo, Juan C; Conde, Blanca; Hempstead, Barbara I; Chao, Moses V; Martín-Zanc 📂 Article 📅 2001 🏛 Nature Publishing Group 🌐 English ⚖ 162 KB

Structural mechanisms of constitutive ac

Structural mechanisms of constitutive activation in the C5a receptors with mutations in the extracellular loops: Molecular modeling study

✍ Gregory V. Nikiforovich; Thomas J. Baranski 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 641 KB

## Abstract Previously we demonstrated by random saturation mutagenesis a set of mutations in the extracellular (EC) loops that constitutively activate the C5a receptor (C5aR) (Klco et al., Nat Struct Mol Biol 2005;12:320–326; Klco et al., J Biol Chem 2006;281:12010–12019). In this study, molecular

Constitutive activity modulation of huma

Constitutive activity modulation of human metabotropic glutamate 5a receptors in HEK293 cells: a role for key amino-terminal cysteine residues

✍ Andreas Mühlemann; Catherine Diener; Christophe Fischer; Jenny Piussi; Andy Stuc 📂 Article 📅 2005 🏛 Nature Publishing Group 🌐 English ⚖ 281 KB