## Abstract The computer program LUDI for automated structureβbased drug design is described. The program constructs possible new ligands for a given protein of known threeβdimensional structure. This novel approach is based upon rules about energetically favourable nonβbonded contact geometries be
β¦ LIBER β¦
A novel conformation optimization model and algorithm for structure-based drug design
β Scribed by Ling Kang; Honglin Li; Xiaoyu Zhao; Hualiang Jiang; Xicheng Wang
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 227 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0259-9791
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