𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A novel cloning system for direct screening using a suicidal strategy

✍ Scribed by Érika V.S.A. Barros; Luiz A.M. Bataus; Fernando F. Valência; Andréa Q. Maranhão; Spartaco Astolfi-Filho

Book ID
117521812
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
298 KB
Volume
179
Category
Article
ISSN
0378-1119

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A novel suicide inhibitor strategy for a
A novel suicide inhibitor strategy for antiparasitic drug development
✍ C. C. Wang 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 488 KB

DL-a-Difluoromethylornithine (DFMO), a suicide inhibitor of eukaryotic ornithine decarboxylase (ODC), has therapeutic activities against African trypanosomiasis. The K, value of DFMO for ODC of Trypanosoma brucei is somewhat higher than that for mouse ODC. The therapeutic efficacy of DFMO cannot the