A Novel Classification of Lewis Acids on the Basis of Activity and Selectivity

✍ Scribed by Shū Kobayashi; Tsuyoshi Busujima; Satoshi Nagayama

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 141 KB
• Volume: 6
• Category: Article
• ISSN: 0947-6539
• DOI: 10.1002/1521-3765(20001002)6:19<3491::aid-chem3491>3.0.co;2-p

✦ Synopsis

Group 3 ± 15 metal chlorides (Lewis acids) were classified on the basis of activity and aldehyde-and aldimineselectivity in an addition reaction of a silyl enol ether. Based on the experimental results, metal chlorides (Lewis acids) were classified as follows: A, active; B, weak; C, inactive for the activation of the aldehyde and/or aldimines. Groups A and B were further divided into A-1 or B-1 (aldehyde-selective), A-2 or B-2 (aldimine-selective), and A-3 or B-3 (neutral). The final classification is as follows: A