A Novel Class of Cycloalkano[ b ]pyridines as Potent and Orally Active Opioid Receptor-like 1 Antagonists with Minimal Binding Affinity to the hERG K + Channel

✍ Scribed by Yoshizumi, Takashi; Takahashi, Hirobumi; Miyazoe, Hiroshi; Sugimoto, Yuichi; Tsujita, Tomohiro; Kato, Tetsuya; Ito, Hirokatsu; Kawamoto, Hiroshi; Hirayama, Mioko; Ichikawa, Daisuke; Azuma-Kanoh, Tomoko; Ozaki, Satoshi; Shibata, Yoshihiro; Tani, Takeshi; Chiba, Masato; Ishii, Yasuyuki; Okuda, Shoki; Tadano, Kiyoshi; Fukuroda, Takahiro; Okamoto, Osamu; Ohta, Hisashi

• Book ID: 126274596
• Publisher: American Chemical Society
• Year: 2008
• Tongue: English
• Weight: 222 KB
• Volume: 51
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm701590h