## Abstract Key steps of the synthesis are the regioselective hydrolysis of biscarboxylate (III), the monoacyl azide formation and subsequent Curtius rearrangement to give isocyanate (VI), and the sequential ring closure to give carbonylbis(dihydrothienopyrrole) (X) (and the carbonylbis(dihydrofuro
A novel class of compounds: synthesis of 5,5′-carbonyl-bis(5,6-dihydro-4H-furo- and thieno-[2,3-c]pyrrol-4-ones)
✍ Scribed by Gani Koza; Metin Balci
- Book ID
- 113928947
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- French
- Weight
- 748 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0040-4020
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## Abstract We hereby report the first preparation of the 5,6‐dihydro‐4__H__‐furo[2,3‐__c__]pyrrol‐4‐one (**3**) and its derivatives starting from methyl 3‐(methoxycarbonyl)furan‐2‐acetate (**8**). The ester functionality connected to the methylene group was regiospecifically converted to the desir
## Abstract The ring closure reaction of methyl 2,3‐bis(chloromethyl)thiophene‐5‐carboxylate with several primary amines gives a series of 5,6‐dihydro‐4__H__‐thieno‐[2,3‐__c__]pyrroles. Oxidation of some of these dihydro compounds, using aqueous hydrogen peroxide in methanol, furnishes the correspo