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A Novel Centrosomal RING-Finger Protein, Dorfin, Mediates Ubiquitin Ligase Activity

✍ Scribed by Jun-ichi Niwa; Shinsuke Ishigaki; Manabu Doyu; Toshiaki Suzuki; Keiji Tanaka; Gen Sobue

Book ID
115587498
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
688 KB
Volume
281
Category
Article
ISSN
0006-291X

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TRIM/RBCC, a novel class of β€˜single prot
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## Abstract The TRIM/RBCC proteins are defined by the presence of the tripartite motif composed of a RING domain, one or two B‐box motifs and a coiled‐coil region. These proteins are involved in a plethora of cellular processes such as apoptosis, cell cycle regulation and viral response. Consistent