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A Novel Catalytic and Highly Enantioselective Approach for the Synthesis of Optically Active Carbohydrate Derivatives

✍ Scribed by Audrain, Hélène; Thorhauge, Jacob; Hazell, Rita G.; Jørgensen, Karl Anker


Book ID
119965475
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
468 KB
Volume
65
Category
Article
ISSN
0022-3263

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Highly Enantioselective Catalytic Alkyny
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## Abstract The development of highly enantioselective catalysts involving Cu(OTf)~2~ and chiral camphorsulfonamides for the alkynylation of ketone is described. The influences of Lewis acids, reaction conditions and chiral ligands on the outcome of the reaction are discussed. The best enantioselec