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A Novel Bioartificial Liver With Culture of Porcine Hepatocyte Aggregates Under Simulated Microgravity

✍ Scribed by Boris Hochleitner; Paul Hengster; Li Duo; Herwig Bucher; Günter Klima; Raimund Margreiter

Book ID
109092805
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
355 KB
Volume
29
Category
Article
ISSN
0160-564X

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We have developed a novel bioreactor based on the observation that isolated porcine hepatocytes rapidly and spontaneously aggregate into spheroids under oscillation conditions. The purpose of this study was to characterize the influence of oscillation frequency (0.125 Hz, 0.25 Hz), cell density (1-1