A novel automated assay for the rapid identification of metastatic breast carcinoma in sentinel lymph nodes
โ Scribed by Sheldon Feldman; Savitri Krishnamurthy; William Gillanders; Mark Gittleman; Peter D. Beitsch; Peter R. Young; Christian J. Streck; Pat W. Whitworth; Edward A. Levine; Susan Boolbol; Linda K. Han; Robert Hermann; Dave S. B. Hoon; Armando E. Giuliano; Funda Meric-Bernstam; for the US One Step Nucleic Acid Amplification Clinical Study Group
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 157 KB
- Volume
- 117
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract ## BACKGROUND The sensitivity of the intraoperative diagnosis of sentinel lymph node (SLN) micrometastases and the metastases of invasive lobular carcinoma (ILC) is low. The goal of the current study was to assess whether the use of intraoperative, rapid immunohistochistochemistry (IHC
## Abstract ## Background Ideally, intraoperative sentinel lymph node (SLN) analysis in breast cancer should be automated, have high concordance with extensive histopathology, and be applicable in any hospital setting. A prospective multicentre evaluation of the one-step nucleic acid amplification
## BACKGROUND. The current report provides results from a large retrospective analysis of intraoperative imprint cytology performed on axillary sentinel lymph nodes (IIC N ) removed over the course of 2137 breast surgeries (4905 lymph nodes). It is hoped that these results may serve as benchmarks
## BACKGROUND. Thirty percent of lymph node negative patients with operable breast carcinoma experience disease recurrence within 10 years. Retrospective serial sectioning of axillary lymph nodes has revealed undetected metastases in 9 -30% of these patients. These occult metastases have been show