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A novel approach to the total synthesis of prostaglandins. Preparation of a stereoisomeric mixture containing (±)-13,14-dihydroprostaglandin E1

✍ Scribed by Donald P. Strike; Herchel Smith


Publisher
Elsevier Science
Year
1970
Tongue
French
Weight
191 KB
Volume
11
Category
Article
ISSN
0040-4039

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A novel approach to a key intermediate i
✍ R.F. Church; R.E. Ireland; J.A. Marshall 📂 Article 📅 1961 🏛 Elsevier Science 🌐 French ⚖ 242 KB

The total synthesis of the naturally occurring triterpene aonocerin was first accomplished by Stork and co-workers 3 via the Alternate approach to a-onocerin No. 1 6% yield to the acetoxy ester(lO), m.p. 121-122"(C,70.67$; H, 9.33%) by successive treatment with diazomethane, sodium borohydride and t