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A Novel Approach to the Synthesis of Amino-Sugars. Routes To Selectively Protected 3-Amino-3-deoxy-aldopentoses Based on Pyridinium Salt Photochemistry

โœ Scribed by Lu, Haiyan; Su, Zhuoyi; Song, Ling; Mariano, Patrick S.


Book ID
118745860
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
68 KB
Volume
67
Category
Article
ISSN
0022-3263

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A new method for synthesis of 3'-end-phosphorylated DNA oligomers via the phosphoramidite method with allyl protection has been developed. This method is particularly useful for the preparation of derivatives with base-labile structures such as oligoDNA-OPO(OH)OCH2CH(R)Z, in which Z is an electron-w