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A Novel Approach to the Hexahydropyrrolo[2,3-b]indole Nucleus: A Synthesis of (±)-Desoxyeseroline

✍ Scribed by Paulo F. Santos; Ana M. Lobo; Sundaresan Prabhakar


Book ID
103408865
Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
142 KB
Volume
36
Category
Article
ISSN
0040-4039

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ChemInform Abstract: Synthesis of the 3a
✍ D. CRICH; E. FREDETTE; W. J. FLOSI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

Synthesis of the 3a-(3-Indolyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3b]indole Core of Leptosins D-F. -The Fischer indole reaction of the previously reported L-tryptophan-derived aldehyde (I) with phenyl hydrazine in the presence of freshly fused zinc chloride provides the core unit (IV) of the leptosin