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A Novel Approach to Protein-Protein Interaction: Complex Formation between the P53 Tumor Suppressor and the HIV Tat Proteins

✍ Scribed by F. Longo; M.A. Marchetti; L. Castagnoli; P.A. Battaglia; F. Gigliani

Book ID
115575980
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
478 KB
Volume
206
Category
Article
ISSN
0006-291X

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## Abstract We recently characterized the interaction between poly(ADP‐ribose) polymerase‐1 (PARP‐1) and the product of the tumor suppressor gene __p53__. We investigated which domains of human PARP‐1 and of human wild‐type (wt) p53 were involved in this protein–protein interaction. We generated ba