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A Novel Approach in Cinnamic Acid Synthesis: Direct Synthesis of Cinnamic Acids from Aromatic Aldehydes and Aliphatic Carboxylic Acids in the Presence of Boron Tribromide

โœ Scribed by Chiriac, C.; Tanasa, F.; Onciu, M.


Book ID
120996566
Publisher
Molecular Diversity Preservation International
Year
2005
Tongue
English
Weight
52 KB
Volume
10
Category
Article
ISSN
1420-3049

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A new direct synthesis of cinnamic acids
โœ Constantin I Chiriac; Fulga Tanasa; Marioara Onciu ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 132 KB

Cinnamic acids have been prepared in 59-86% yields by a new direct synthesis from aromatic aldehydes and aliphatic carboxylic acids in the presence of sodium borohydride and N-methyl-2-pyrrolidinone (NMP) as solvent, at reflux (185-190ยฐC), for 9-12 hours. Without sodium borohydride, this reaction is