Synthesis of (โ)-Cytoxazone, a Novel Cyt
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Masanori Seki; Kenji Mori
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Article
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1999
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John Wiley and Sons
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English
โ 210 KB
๐ 1 views
Cytoxazone [(4R,5R)-(-)-5-hydroxymethyl-4-(4-methoxyphen-employing the Sharpless asymmetric dihydroxylation as the key reaction in 26% overall yield (7 steps). yl)-2-oxazolidinone, 1], a new immunosuppressant, was synthesized by starting from p-methoxycinnamyl alcohol (2) In 1998 Osada and co-worke