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A novel and efficient synthesis of oxazoles from tosylmethylisocyanide and carbonyl compounds

โœ Scribed by A.M. van Leusen; B.E. Hoogenboom; H. Siderius

Publisher
Elsevier Science
Year
1972
Tongue
French
Weight
140 KB
Volume
13
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES

A new synthesis of thiazoles from tosylm
A new synthesis of thiazoles from tosylmethylisocyanide and carboxymethyl dithioates
โœ O.H. Oldenziel; A.M. van Leusen ๐Ÿ“‚ Article ๐Ÿ“… 1972 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 96 KB

In a previous series of papers 293 the synthetic utility of tosylmethylisocyanide (TosMIC, I) has been advocated. TosMIC reacts, under basic conditions, with carbonyl compounds to provide in good yields oxazoles (III, X=0), or 4-tosyl-substituted oxazoles (IV, X=0), depending on the nature of Y in I