A novel and concise synthesis of aminocyclopentitols and 1-deoxynojirimycin via radical cyclization of oxime ethers
✍ Scribed by Toshiko Kiguchi; Kazumi Tajiri; Ichiya Ninomiya; Takeaki Naito; Hajime Hiramatsu
- Book ID
- 103398653
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 178 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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A Concise Synthesis of Rigidified β-Amino Acids via Sulfanyl Radical Addition-Cyclization of Oxime Ethers and Hydrazones. -Sulfanyl radical cyclization of alkenyl-tethered oxime ethers and hydrazones (I) provides cis/trans mixtures of the cyclized products (III) and (IV). The cyclopentylamines (III
AbstractÐStannyl radical addition±cyclization of oxime ethers derived from d-glucose, d-galactose, and d-xylose proceeded smoothly to afford alkoxyamino alcohols which were effectively converted into two types of glycosidase inhibitors or its candidates such as aminocyclitols, 1-deoxynojirimycin, an
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