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A Novel Adhesion Molecule Plays a Critical Role in T Cell Migration to Inflamed Skin

✍ Scribed by Gainers, M.E.; Descheny, L.; Dimitroff, C.J.

Book ID: 119278532
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 51 KB
Volume: 119
Category: Article
ISSN: 1097-6825
DOI: 10.1016/j.jaci.2006.11.570

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## Abstract ## BACKGROUND To redirect cytotoxic T cells to target a broad range of adenocarcinomas, the authors constructed a novel, recombinant, bispecific antibody, E3Bi, directed at the tumor‐associated antigen, epithelial cell adhesion molecule (EpCAM), and the CD3 receptor on T cells. ## MET