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A novel access to pyrido[4,3-d]pyrimidine scaffold via Staudinger/intramolecular aza-Wittig reaction of 5-acyl-4-(β-azidoalkyl)-1,2,3,4-tetrahydropyrimidin-2-ones

✍ Scribed by Fesenko, Anastasia A.; Shutalev, Anatoly D.


Book ID
125827422
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
763 KB
Volume
70
Category
Article
ISSN
0040-4020

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✍ Sheng-Zhen Xu; Min-Hui Cao; Chang-Shui Chen; Ming-Wu Ding 📂 Article 📅 2009 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 89 KB

## Abstract magnified image The carbodiimides **2**, obtained from reactions of iminophosphorane **1** with isocyanates, reacted with hydrazine to give selectively 3‐amino‐2‐arylaminobenzothieno[3,2‐__d__]pyrimidin‐4(3__H__)‐ones **4**. Reactions of **4** with triphenylphosphine, hexachloroethane,