A Note on Power Approximations for the Transmission/Disequilibrium Test
β Scribed by Michael Knapp
- Book ID
- 117852780
- Publisher
- American Society of Human Genetics
- Year
- 1999
- Tongue
- English
- Weight
- 211 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0002-9297
- DOI
- 10.1086/302334
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π SIMILAR VOLUMES
Due in part to an influential paper by Risch and Merikangas [(1996) Science 273:1516-1517], which suggested that disequilibrium tests would have greater power to detect genes of small effect than would linkage tests, interest in the use of the Transmission Disequilibrium Test (TDT) as an analysis to
## Abstract The transmission/disequilibrium test (TDT) for binary traits is a powerful method for detecting linkage between a marker locus and a trait locus in the presence of allelic association. The TDT uses information on the parentβtoβoffspring transmission status of the associated allele at th