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A NOTCH4 association with multiple sclerosis is secondary to HLA-DR*1501

✍ Scribed by K. Duvefelt; M. Anderson; A. Fogdell-Hahn; J. Hillert

Book ID: 110891954
Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 87 KB
Volume: 63
Category: Article
ISSN: 0001-2815
DOI: 10.1111/j.1399-0039.2004.00135.x

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## Abstract Susceptibility to multiple sclerosis (MS) is associated genetically with human leucocyte antigen (HLA) class II alleles, including DRB1\*1501, DRB5\*0101, and DQB1\*0602, and it is possible that these alleles contribute to MS through an enhanced ability to present encephalitogenic myeli