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A nonpeptidic agonist ligand of the human C5a receptor: Synthesis, binding affinity optimization and functional characterization

✍ Scribed by S.E. de Laszlo; E.E. Allen; B. Li; D. Ondeyka; R. Rivero; L. Malkowitz; C. Molineaux; S.J. Siciliano; M.S. Springer; W.J. Greenlee; N. Mantlo

Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 297 KB
Volume: 7
Category: Article
ISSN: 0960-894X
DOI: 10.1016/s0960-894x(96)00606-3

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✦ Synopsis

The structural optimization for binding affinity and attempted modification of agonist function of a nonpeptide ligand of the human C5a receptor is described.

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