Design of a stirred multiwell bioreactor
โ
Camilla Luni; Monica Zagallo; Lara Albania; Martina Piccoli; Michela Pozzobon; P
๐
Article
๐
2011
๐
American Institute of Chemical Engineers
๐
English
โ 923 KB
Besides having a metabolic role, oxygen is recognized as an important signaling stimulus for stem cells. In hematopoiesis, hypoxia seems to favor stem cell self-renewal. In fact, longterm repopulating hematopoietic stem cells reside in bone marrow at concentrations as low as 1% oxygen. However, O 2