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A non-invasive test for prenatal diagnosis based on fetal DNA present in maternal blood: a preliminary study

✍ Scribed by Ravinder Dhallan; Xin Guo; Sarah Emche; Marian Damewood; Philip Bayliss; Michael Cronin; Julie Barry; Jordan Betz; Kara Franz; Katie Gold; Brett Vallecillo; John Varney


Book ID
117300548
Publisher
The Lancet
Year
2007
Tongue
English
Weight
696 KB
Volume
369
Category
Article
ISSN
0140-6736

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Fetal erythroblasts circulating in maternal blood are important candidate cells for non-invasive prenatal diagnosis. We have cultured erythroblasts from 16 maternal blood samples, both with and without prior enrichment by magnetic activated cell sorting (MACS), in a semi-solid medium containing grow