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A non-haem iron centre in the transcription factor NorR senses nitric oxide

✍ Scribed by D'Autréaux, Benoît; Tucker, Nicholas P.; Dixon, Ray; Spiro, Stephen


Book ID
109894651
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
355 KB
Volume
437
Category
Article
ISSN
0028-0836

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## Abstract Nitric oxide (NO) is cytotoxic for human SH‐SY5Y neuroblastoma cells. While nuclear condensation was visible in cells treated with nitric oxide donors, we observed that the plasma membrane remained intact, indicating that NO induced apoptotic cell death. We analyzed the NO‐induced apopt