Efficient generation of double heterolog
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Dennis Hoffmann; Oliver Wildner
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Article
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2006
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BioMed Central
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English
⚖ 816 KB
## Background Oncolytic adenoviruses are promising agents for the multimodal treatment of cancer. However, tumor-selectivity is crucial for their applicability in patients. Recent studies by several groups demonstrated that oncolytic adenoviruses with tumor-/tissue-specific expression of the E1 and