✦ LIBER ✦
A new variant of human erythrocyte G6PD occurring at a high frequency amongst the population of two villages in The Gambia, West Africa
✍ Scribed by S. G. Welch; I. A. McGregor; K. Williams
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 317 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0340-6717
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✦ Synopsis
During the course of a large survey of red cell G6PD genotypes in The Gambia, a slow electrophoretic variant with reduced enzyme activity was found to occur at a high frequency. This variant, G6PD Gambia, was found in the following genotypic combinations: males; G6PDGam, females; G6PDA+/Gam, G6PDB+/Gam, and G6PDA-/Gam. From the electrophoretic mobility and kinetic characteristics it was concluded that G6PD Gambia was a hitherto unreported variant of G6PD. The frequency of the G6PDGam gene amongst the 1109 individuals examined was 0.024.