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A new vaginal delivery system of amphotericin B: a dispersion of cationic liposomes in a thermosensitive gel

✍ Scribed by Kang, June-Woo; Davaa, Enkhzaya; Kim, Ye-Tae; Park, Jeong-Sook

Book ID
115442599
Publisher
Informa plc
Year
2010
Tongue
English
Weight
839 KB
Volume
18
Category
Article
ISSN
1061-186X

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✍ I. Ahmad; A. K. Sarkar; B. K. Bachhawat πŸ“‚ Article πŸ“… 1989 πŸ› Springer 🌐 English βš– 395 KB

The efficacy and toxicity of free and liposome intercalated amphotericin-B (Amp-B) in controlling Aspergillosis, caused by Aspergillus fumigatus in BALB/c mice were studied. Liposomal Amp-B had higher LD50 (8.1 mg/kg) as compared to that of the free drug (1.2 mg/kg). An improvement in the therapeuti