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A new tyrosinase epitope recognized in the HLA-B*4002 context by CTL from melanoma patients

✍ Scribed by Yann Godet; Annabelle Bonnin; Yannik Guilloux; Virginie Vignard; Dirk Schadendorf; Brigitte Dreno; Francine Jotereau; Nathalie Labarriere


Book ID
105967471
Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
484 KB
Volume
58
Category
Article
ISSN
0340-7004

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## Abstract Cytotoxic T lymphocytes (CTL) reactive with human melanoma tumor cells occasionally display cross‐reactivity with normal melanocytes. Previously, we identified the melanocyte lineage‐specific antigen gp100 that is expressed by both melanoma cells and normal melanocytes, as a target anti