A New Tool in Peptide Engineering: A Photoswitchable Stilbene-type β-Hairpin Mimetic

Tuning the β-turn segment in designed pe

Tuning the β-turn segment in designed peptide β-hairpins: Construction of a stable type I′ β-turn nucleus and hairpin–helix transition promoting segments

✍ Rajkishor Rai; Srinivasarao Raghothama; Rajagopalan Sridharan; Padmanabhan Balar 📂 Article 📅 2007 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 553 KB

## Abstract Designed octapeptides Boc‐Leu‐Val‐Val‐Aib‐^D^Xxx‐Leu‐Val‐Val‐OMe (^D^Xxx = ^D^Ala, 3a;^D^Val, 3c and ^D^Pro, 5a) and Boc‐Leu‐Phe‐Val‐Aib‐^D^Ala‐Leu‐Phe‐Val‐OMe (3b) have been investigated to construct models of a stable type I′ β‐turn nucleated hairpin and to generate systems for invest