A major problem in the analysis of clinical trials is missing data from patients who drop out of the study before the predetermined schedule. In this paper we consider the situation where the outcome measure is a continuous variable and the final outcome at the end of the study is the main interest.
A New Test for Cross-Over Clinical Trials with Order Effects
โ Scribed by Chap T. Le
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 179 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0323-3847
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๐ SIMILAR VOLUMES
We consider a clinical trial model comparing an experimental treatment with a control treatment when the responses are binary. For fixed significance level and power, we compare the expected number of treatment failures for two designsthe randomized play-the-winner rule and the triangular test. The
standardized I\* , as described in Oden and Oden et al. The following lines of Dr. Tango's tables are affected: i) I\* normal approximation and I\* chi-square approximation for alpha"0)05 and alpha"0)01 in Tango's tables I and III. ii) I\* critical values for alpha"0)05 and alpha"0)01 in Tango's Tab