The reaction of demethylation mediated by cytochrome P450 (CYP) leads to the equimolar production of demethylated metabolite and formaldehyde. From a 13C-substrate labeled on a carbon of the methyl moiety, [13C]formaldehyde (H13CHO) is liberated. A highly sensitive and specific assay involving the o
β¦ LIBER β¦
A new technique for the detection of metabolites labelled by the isotope 13C using mass fragmentography
β Scribed by M. Sano; Y. Yotsui; H. Abe; S. Sasaki
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 235 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1076-5174
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