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A new synthesis of δ-lactones from oxetanes

✍ Scribed by Masahiko Yamaguchi; Keisuke Shibato; Ichiro Hirao

Book ID
104242706
Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
224 KB
Volume
25
Category
Article
ISSN
0040-4039

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✦ Synopsis

Oxetanes were reacted with lithium enolates generated from esters or amides in the presence of boron trifluoride etherate to give S-hydroxyes-ters or amides in high yield, which were hydrolyzed and converted to 6-lactones.

Lactones are one of the most familiar class of compounds in organic chemistry

1)

and many methods were reported for the synthesis of the compounds

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