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A new synthesis of substituted pyrazoles from 1,4-dianions of phenylhydrazones having an α-hydrogen

✍ Scribed by Robert S. Foote; Charles F. Beam; Charles R. Hauser


Book ID
112122167
Publisher
Journal of Heterocyclic Chemistry
Year
1970
Tongue
English
Weight
236 KB
Volume
7
Category
Article
ISSN
0022-152X

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Studies on enaminonitriles: A new synthe
✍ Said Ahmed Soliman Ghozlan; Ismail Abdelshafy Abdelhamid; Mohamed Hilmy Elnagdi; 📂 Article 📅 2005 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 88 KB

3-Diethylaminoacrylonitrile (1) reacts with hydrazonyl halides (2a-d) to yield 1,3-disubstituted pyrazole-4-carbonitriles 5a-d. The acetyl 1-p-chlorophenylpyrazole-4-carbonitrile (5a) condensed with hydrazine hydrate to yield the bishydrazone 10 and with dimethylformamide dimethylacetal to yield 1-a