A New Synthesis of Nornicotine and Nicotine
β Scribed by Craig, Lyman C.
- Book ID
- 120424788
- Publisher
- American Chemical Society
- Year
- 1933
- Tongue
- English
- Weight
- 298 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
## Abstract The synthesis of ^15^Nβlabelled nornicotine **2** and ^15^Nβlabelled nicotine **1** is described via the reductive aminocyclization of a 1,4βketoaldehyde with a corresponding amine in the presence of sodium cyanoborohydride. Yields of 30% and 26%, respectively, were obtained from 3βbrom
Division of Clinical Pharmacology and Experimental Therapeutlcs of the Department of Medicine San man&sco General Hospital Medical Center and the Department of Medicine and Langley Porter Psychiatric Institute untversity of CaKOmia. san Francisco san Francisco. California 94143 We descrlbe methods f