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A new synthesis of dl-muscopyridine based on the regioselective cyclopentenone annulation

โœ Scribed by Hiroyuki Saimoto; Tamejiro Hiyama; Hitosi Nozaki


Book ID
103406483
Publisher
Elsevier Science
Year
1980
Tongue
French
Weight
135 KB
Volume
21
Category
Article
ISSN
0040-4039

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The reaction of the dilithio derivative of dimethyl cis-4-cyclohexen-1,2-dicarboxylate with 3substituted propiolic acid phenyl esters proceeds via an unusual mechanistic path to generate fused bicyclic 2cyclopentenones in a single step. The first total synthesis of a member of the gingkolide family