A novel, one-step annulation process for
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E.J Corey; Wei-guo Su
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Article
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1987
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Elsevier Science
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French
โ 214 KB
The reaction of the dilithio derivative of dimethyl cis-4-cyclohexen-1,2-dicarboxylate with 3substituted propiolic acid phenyl esters proceeds via an unusual mechanistic path to generate fused bicyclic 2cyclopentenones in a single step. The first total synthesis of a member of the gingkolide family