Asymmetric cyclopropanation of chiral (1
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Wanda H Midura; Marian MikoΕajczyk
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Article
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2002
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Elsevier Science
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French
β 292 KB
E-(S)-(1-Dimethoxyphosphoryl-2-phenyl)vinyl p-tolyl sulfoxide 3 was found to undergo cyclopropanation with sulfur ylides [dimethyl(oxo)sulfonium methylide, diphenyl sulfonium isopropylide and ethyl (dimethylsulfuranylidene)acetate (EDSA)] in a highly diastereoselective manner. The major diastereomer