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A new synthesis of 7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide

✍ Scribed by Stanley C. Bell; Ronald J. Mccaully; Scott J. Childress


Book ID
112121678
Publisher
Journal of Heterocyclic Chemistry
Year
1967
Tongue
English
Weight
279 KB
Volume
4
Category
Article
ISSN
0022-152X

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## Abstract Two benzodiazepines, Diazepam and Flunitrazepam, labeled with carbon‐14 in position 5 of the diazepine ring have been synthesized. Use of a condensation between iminochlorides and ^14^C‐benzonitriles, followed by exhaustive methylation of the resulting quinazolines and hydrolyses is des