A practical synthesis of new S,N-disubst
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Tomasz Pospieszny; ElΕΌbieta Wyrzykiewicz
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Article
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2008
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Elsevier Science
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French
β 165 KB
a b s t r a c t 5-(4-Methylpiperidino)methyl-2-thiouracil (1) has been obtained via the Mannich reaction between 2-thiouracil, paraformaldehyde, and a cyclic secondary amine such as 4-methylpiperidine (4-MP) in ethanol. New S,N(1)-di-o-(m-and p-)bromo-(nitro-) benzyl-substituted derivatives have bee