Reversal of breast cancer resistance pro
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Ken Shiozawa; Mikio Oka; Hiroshi Soda; Megumi Yoshikawa; Yoji Ikegami; Junji Tsu
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Article
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2003
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John Wiley and Sons
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French
β 165 KB
π 1 views
## Abstract Breast cancer resistance protein (BCRP/ABCG2) of an ATPβbinding cassette halfβtransporter confers resistance against mitoxantrone and camptothecin derivatives of topotecan and irinotecan. Novobiocin, a coumermycin antibiotic, is known to enhance anticancer drug sensitivity of cancer cel